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Category:Remixes by DJ S.K.AGnRH-A receptor mRNA and protein expressions are upregulated in human breast carcinoma tissue: potential roles in the pathogenesis and diagnosis of breast carcinoma.
Gonadotropin-releasing hormone (GnRH) is a neuropeptide with various roles in regulating reproductive systems. However, expression of GnRH-receptor in human breast carcinomas has not been studied. In this study, GnRH-A receptor mRNA and protein expressions in human breast carcinomas were examined. Using a polymerase chain reaction (PCR) method, GnRH-A receptor mRNA was detected in 13 of 21 (62%) human breast carcinoma tissues, but was not detected in 18 breast carcinoma tissues in which human epidermal growth factor receptor 2 (HER2) was amplified. In contrast, GnRH-A receptor mRNA was not detected in the normal breast tissues. Quantitative real-time reverse transcription-PCR analysis showed that GnRH-A receptor mRNA levels in human breast carcinoma tissue were higher than those in the normal breast tissues. Immunohistochemical analysis demonstrated that GnRH-A receptor was expressed in both luminal and/or myoepithelial cells in human breast carcinoma tissues, and that the GnRH-A receptor protein expression level was also upregulated in human breast carcinomas as compared with the normal breast tissues. These results suggest that GnRH-A receptor may have important roles in the pathogenesis and diagnosis of human breast carcinoma.Q:
What does "double" mean in the expression (double) 1.0/3?
Is it (double) 1.0/3.0 or 1/3.0 or (double) 1/3?
Which one is correct?
A:
1/3.0 is the format you want
A:
The word "double" is not there for you. The problem is the ambiguity between the integer 1 and the decimal 1.0. The 1/3.0 is the same as 1/3, and so the answer is 1/3.0.
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Branding that stands the test of time
September 23, 2013
By Michael Sleeman, of Janelle Organisational Partners
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